Insights in Blood Pressure

Depression in patients with peripheral arterial disorder

Background/objective:The aim of the present study wasto examine the association of depressive symptomatology with PAD, independently of traditional risk factors.

Method: The sample comprised of 300 individuals (M_age=65.3±8.7 years, 61.0% female) recruited from the offices of 33 general practitioners. Based on at-rest ankle-brachial index (ABI) values and claudication symptoms, four subsamples were formed: clear PAD-positive, clear PAD-negative, ABI-negative but symptomatic, and anon-compressible-artery group. The role of depression (assessed by a shortened version of the BDI), in predicting PAD status was examined using multinomial logistic regression analysis – controlled for sex, age, hypertonia, diabetes, smoking, hazardous drinking, and body mass index.

Results: Depressive symptomatology was significant in predicting PAD status for the clear PAD-positive(OR: 1,48 (1,33-165) ), theABI-negative but symptomatic(OR: 1,37 (1,22-1,53)) andfor the non-compressible-artery group.

Author(s):

Dr.Gergely Tóth-Vajna

Institute of Behavioural Sciences, Semmelweis University, 1089 Budapest

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