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Contrast Induced Nephropathy after Radial or Femoral Access for Invasive Management of Acute Coronary Syndrome

Background: Percutaneous coronary intervention is now the best way of management of acute coronary syndrome (ACS). Contrast induced nephropathy is a serious complication and greatly dependent on several factors. It is still unclear whether the vascular access affects CIN risk.

Objective: To study the impact of Radial Access (RA) compared with Femoral Access (FA) on developing contrast-induced nephropathy (CIN) in patients undergoing invasive management of acute coronary syndrome (ACS).

Methods: Sixty patients eligible for invasive management of ACS at cardiology department (Menoufia University hospital and National Heart Institute) were randomized into two groups. Group I:  included 30 patients with femoral approach and Group II: included 30 patients with radial approach. The occurrence of CIN estimated by KDIGO definition (absolute increase in serum creatinine (SCr) by ≥ 0.5 mg/dl within 48 hours; or increase in SCr to ≥ 25% of baseline) was estimated in both groups.

Results: Only 9 patients (15 %) developed CIN, 5 patients (55.6%) of them underwent PCI through FA without statistically significant difference between the two approaches.

Conclusion: CINis considered a potential complication


Dr. Ahmed Abdelbaky Abdel Aziz

Retired, Cairo, Egypt

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